Macintosh HD\Applications\Microsoft Office 2008 Note the 'Path' that is listed in the error message, and then close the error message box. When the error message is displayed, view the comments under 'Problem Details and System Configuration.'. Resolution Step 1: Check the program path This error occurs if the Office program was moved or duplicated. Be sure to install any available updates for the application and Mac OS X. You may need to reinstall the application. When you try to start any Office for Mac applications (Microsoft Word, Microsoft Excel, Microsoft PowerPoint, Microsoft Entourage, or Microsoft Outlook for Mac) in Mac OS X 10.6.x (Snow Leopard), you receive the following error message: Microsoft cannot be opened because of a problem.Check with the developer to make sure Microsoft works with this version of Mac OS X.
For more information about this change, read this blog post. Office 365 ProPlus is being renamed to Microsoft 365 Apps for enterprise.